crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 831603

Časopis

Autori: Fernando Pereira Vasconcelos, Daniel; Rodolfo Pereira da Silva, Felipe; Moara e Silva Conceição Pinto; Lima Barreto do Nascimento, Maria Luísa; Lucas de Araújo Bastos Santana; Grazielle Souza, Ingrid; Kelves Miranda de Souza, Luan; Martins Oliveira, Natássia Cristina; Duarte Novaes, Pedro; Rocha Marques, Marcelo; André Luiz dos Reis Barbosa; Rolim Medeiros, Jand-Venes; Mikolašević, Ivana; Mani, Arya; Jefferson Soares de Oliveira
Naslov: Decrease of Pericytes is Associated With Ligature-Induced Periodontitis Liver Disease in Rats
( Decrease of Pericytes is Associated With Ligature-Induced Periodontitis Liver Disease in Rats )
Izvornik: Journal of periodontology (0022-3492) 88 (2016), 2; e49-e57
Vrsta rada: članak
Ključne riječi: periodontal disease ; steatosis ; glutathione ; malondialdehyde.
( periodontal disease ; steatosis ; glutathione ; malondialdehyde. )
Sažetak:
The aim of this study was to investigate the association between induced periodontitis and the damages caused through its systemic effects on the liver. Twenty rats were divided into two groups: control and periodontitis. The following parameters were evaluated: Gingival Bleeding Index (GBI), Probing Pocket Depth (PPD), Myeloperoxidase (MPO) activity, Alveolar Bone Loss (ABL) for periodontal tissues ; histopathological examination of gingival and liver tissues ; immunohistochemistry to positive cell for neural/glial antigen 2 (NG2) expressed in hepatic pericytes, glutathione (GSH) and malondialdehyde (MDA) concentrations in liver ; serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). GBI, PPD, MPO, ABLs and histopathological examinations demonstrated the development of periodontitis. There was a significant increase in microvesicular steatosis in periodontitis vs. control group, this was accompanied by a marked significantly reduction in NG2+ pericytes, while the level of transaminases remained unchanged. The periodontitis group had significantly lower GSH and higher MDA concentration in the liver compared with the control group. Our results suggest that the induced periodontitis promotes steatosis and reduction of hepatic pericytes, through the increase oxidative stress and lipid peroxidation.
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://www.joponline.org/doi/abs/10.1902/jop.2016.160392
Broj citata:
Altmetric:
DOI: 10.1902/jop.2016.160392
URL cjelovitog teksta:
Google Scholar: Decrease of Pericytes is Associated With Ligature-Induced Periodontitis Liver Disease in Rats
Upisao u CROSBI: Sanjin Rački (sanjin.racki@uniri.hr), 7. Ruj. 2016. u 00:30 sati



  Verzija za printanje   za tiskati


upomoc
foot_4