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Pregled bibliografske jedinice broj: 268554

Zbornik radova

Autori: Cvijanović, Olga; Kristofić, Ines; Španjol, Josip; Zoričić, Sanja; Marić, Ivana; Bobinac, Dragica
Naslov: Bone structure of the iliac crest and lumbar spine: a histomorphometric study of adult population in Croatia
Izvornik: Bone / Baron, Roland (ur.). - New York, SAD : Elsevier Science Inc. , 2001. S197-S197.
ISSN: 8756-3282
Skup: 1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society
Mjesto i datum: Madrid, Španjolska, 05.-10.06.2001.
Ključne riječi: bone histomorphometric parameters; iliac crest; lumbar spine; humans
Sažetak:
The aim of this study was to compare vertical 7 mm thick cylinders of vertebral (L3) and iliac trabecular bone (anterior, posterior, lateral) obtained from 40 normal cadavers aged from 40 to 80 years (20 females and 20 males). Undecalcified trabecular bone samples were embedded in MMA, cut in 7 microm thick sections and stained with TB and Goldner trichrome. Histomorphometric analysis was performed on an image analyzed (VAMS, Issa, zAGreb), and the following parameters were determined: Trabecular bone volume (BV/TV), surface density (BC/TV), trabecular thickness (Tb, Th), number (Tb.N) and separation (Tb.Sp), osteoid thickness (O.Th), volume (OV/BV) and surface (OS/BS). Iliac crest and lumbar vertebra bone samples were compared within each group and between different age-related groups. Men and women within the age range 60 to 80 yr had significantly increased O.Th (p<0.001), OV/BV (p<0.005) and OS/BS (p<0.001) in lumbar vertebrae. Moreover, Tb.S ((p<0.001) was higher in lumbar bone, while BV/TV (p<0.001) and Tb.Th (p<0.005) were greater in men iliac crest. BV/TV (p<0.05), BS/TV (p<0.001), and Tb.N (p<0.001), determined from both lumbar and iliac bone samples, were found significantly increased in a group of younger women (40-60 yr) while Tb.Sp (p<0.005) was lesser, when compared with a group of elderly women. Similarly, in a group of younger men we found BV/TV (p<0.001) and Tb.Th (p<0.005) greater while Tb.Sp (p<0.001) was lesser when compared to elderly men. These results indicate that age-related changes in bone microarchitecture more dramatically affect the vertebrae and less the iliac crest bone. We suggest that increased O.Th, OV/BV, OS/BS vertebral values in elderly women reflect the initial bone repairment, following trabecular microfractures.
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bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 0062075
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti



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