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Pregled bibliografske jedinice broj: 302426

Časopis

Autori: Brekalo Pršo, Ivana; Kocjan, Willy; Šimić, Hrvoje; Brumini, Gordana; Pezelj-Ribarić, Sonja; Borčić, Josipa; Ferreri, Silvio; Miletić Karlović, Ivana
Naslov: Tumor Necrosis Factor-Alpha and interleukin 6 in Human Periapical Lesions
Izvornik: Mediators of Inflammation (0962-9351) 38210 (2007), 1; 1-4
Vrsta rada: članak
Ključne riječi: tumor necrosis factor-alpha; interleukin 6; human periapical lesions
Sažetak:
Aim. The aim of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-α ) and interleukin-6 (IL-6) in human periapical lesions. Subjects and methods. Samples were obtained from three groups of teeth: symptomatic teeth, asymptomatic lesions, and uninflamed periradicular tissues as a control. Results. TNF-alpha levels were significantly increased in symptomatic lesions compared to control. Group with asymptomatic lesions had significantly higher concentrations compared to control. There were no significant differences in TNF-alpha levels between symptomatic and asymptomatic lesions. In group with symptomatic lesions, IL-6 levels were significantly higher than in group with asymptomatic lesions. The IL-6 levels in symptomatic group also showed significantly higher concentration in comparison with control group. In asymptomatic group, the IL-6 level had significantly higher concentrations compared to control. Conclusion. These results indicate that symptomatic lesions represent an immunologically active stage of disease, and asymptomatic lesions are the point from which the process advances toward healing.
Projekt / tema: 065-0650444-0418, 062-0650444-0442, 062-0650446-0499
Izvorni jezik: ENG
Current Contents: DA
Citation Index: DA
Ostale indexne publikacije: Index Medicus
Kategorija: Znanstveni
Znanstvena područja:
Stomatologija
Tiskani medij: da
URL Internet adrese: http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1804300&blobtype=pdf
Google Scholar: Tumor Necrosis Factor-Alpha and interleukin 6 in Human Periapical Lesions
Upisao u CROSBI: Sonja Pezelj-Ribarič (Sonja.Pezelj-Ribaric@medri.hr), 17. Srp. 2007. u 10:38 sati



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