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Pregled bibliografske jedinice broj: 328742

Časopis

Autori: Pezelj-Ribarić, Sonja; Prpić, Jelena; Miletić, Ivana; Brumini, Gordana; Šimunović-Šoškić, Marica; Anić, Ivica
Naslov: Association between oral lichenoid reactions and amalgam restorations
Izvornik: Journal of the European Academy of Dermatology and Venereology (0926-9959) 22 (2008), 10; 1163-1167
Vrsta rada: članak
Ključne riječi: amalgam restorations; oral lichenoid reactions
Sažetak:
The aim of this study was to perform a clinical assessment of the association between oral lichenoid reactions (OLR) and amalgam restorations and to determine the salivary concentrations of interleukin-6 (IL-6) and IL-8 before and after replacement of the amalgam restorations. The study included 20 patients with OLR and 20 healthy volunteers, who were examined between 2001 and 2005 at the Oral Medicine Unit of the Medical Faculty University of Rijeka. All patients were skin patch tested by an experienced physician. Saliva samples were collected, prepared and analysed for IL-6 and IL-8 concentrations using enzyme-linked immunosorbent assay. Sixteen out of 20 patch-tested patients showed a sensitization to inorganic mercury or amalgam. Total replacement of all amalgam fillings was carried out on 20 patients with fillings based on composite resin, gold, porcelain or a combination of these. Sixteen out of 20 patients showed complete healing of OLR ; three patients had marked improvement, whereas one patient showed no improvement. Levels of IL-6 detected before replacement were significantly higher than IL-6 levels following the replacement (P = 0.003). The IL-8 levels measured before replacement procedure were significantly higher than the IL-8 levels after replacement of the fillings (P < 0.001). On the basis of clinical observations, restorative therapy resulted in tissue healing. Following the replacement of amalgam fillings with fillings based on other restorative materials, levels of both IL-6 and IL-8 shifted towards normal, as measured in healthy subjects.
Projekt / tema: 062-0650444-0442, 065-0650444-0418
Izvorni jezik: ENG
Rad je citiran u
bazama podataka:
Current Contents Citation Index
Web of Science: Science Citation Index Expanded
MEDLINE
Web of Science: Science Citation
Scopus
Kategorija: Znanstveni
Znanstvena područja:
Dentalna medicina
Puni text rada: 328742.j.1468-3083.2008.02736.pdf
URL Internet adrese: http://www3.interscience.wiley.com/cgi-bin/fulltext/120123210/PDFSTART
Broj citata:
Altmetric:
DOI: 10.1111/j.1468-3083.2008.02736.x
URL cjelovitog teksta:
Google Scholar: Association between oral lichenoid reactions and amalgam restorations
Upisao u CROSBI: sonjap@medri.hr (sonjap@medri.hr), 14. Tra. 2008. u 11:37 sati



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