crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 490849

Časopis

Autori: Hearnden, Vanessa; Sankar, Vidya; Hull, Katrusha; Vidović Juras, Danica; Greenberg, Martin; Kerr, Ross A.; Lockhart, Peter B.; Patton, Lauren L.; Porter, Stephen; Thornhill, Martin
Naslov: New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery
Izvornik: Advanced drugs delivery reviews (0169-409X) 64 (2012), 1; 16-28
Vrsta rada: pregledni rad
Ključne riječi: oral mucosa; drug delivery technology; trans-mucosal; local drug delivery; systemic drug delivery; formulations; targeting; mucoadhesives; polymersomes
Sažetak:
The oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first-pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technological advances in mucoadhesives, sustained drug release, permeability enhancers and drug delivery vectors are increasing the efficient delivery of drugs to treat oral and systemic diseases. When treating oral diseases, these advances result in enhanced therapeutic efficacy, reduced drug wastage and the prospect of using biological agents such as genes, peptides and antibodies. These technologies are also increasing the repertoire of drugs that can be delivered across the oral mucosa to treat systemic diseases. Trans-mucosal delivery is now a favoured route for non-parenteral administration of emergency drugs and drugs where a rapid onset of action is required. Furthermore, advances in drug delivery technology are bringing closer the possibility of transmucosal systemic delivery of biological agents.
Projekt / tema: 065-0650445-0485
Izvorni jezik: ENG
Rad je citiran u
bazama podataka:
Web of Science: Science Citation
Current Contents Citation Index
Scopus
Web of Science: Science Citation Index Expanded
MEDLINE
Kategorija: Stručni
Znanstvena područja:
Dentalna medicina,Farmacija
URL Internet adrese: http://www.sciencedirect.com/science/article/pii/S0169409X11000433
http://www.ncbi.nlm.nih.gov/pubmed/21371513
Broj citata:
Altmetric:
DOI: 10.1016/j.addr.2011.02.008
URL cjelovitog teksta: http://ac.els-cdn.com/S0169409X11000433/1-s2.0-S0169409X11000433-main.pdf?_tid=52061d4c-d7ff-11e2-9173-00000aab0f6c&acdnat=1371550417_526ad97ff0193f465edaf69f74e36b32
Google Scholar: New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery
Upisao u CROSBI: djuras@sfzg.hr (djuras@sfzg.hr), 11. Stu. 2010. u 13:17 sati



  Verzija za printanje   za tiskati


upomoc
foot_4