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Pregled bibliografske jedinice broj: 536968

Časopis

Autori: Vučićević Boras, Vanja; Rogić, Dunja; Brailo, Vlaho; Vidović Juras, Danica; Glažar, Irena; Muhvić-Urek, Miranda
Naslov: Sialochemistry in Patients with Oral Lichen Planus
Izvornik: Acta stomatologica Croatica (0001-7019) 45 (2011), 3; 184-189
Vrsta rada: članak
Ključne riječi: Saliva; Lichen Planus; Oral; Salivary Proteins and Peptides
Sažetak:
Objective: It is well known that certain salivary constituents might be disturbed in patients suffering from oral lichen planus (OLP), however, the results of the published studies are inconsistent. The aim of this study was to assess the concentrations of salivary analytes because most of them are part of salivary enzymes which maintain integrity of the oral mucosa which is compromised in OLP patients. Materials and Methods: In 25 patients with OLP (73±1.4 yrs) and in the 24 controls (24±3.7yrs) levels of total proteins, amylase, salivary magnesium, calcium, copper, chloride, phosphate, potassium and sodium were determined. Total proteins were determined by pyrogalol colorimetric method. Amylase levels were determined by continued colorimetric method. Salivary sodium, potassium and chloride were determined by indirect potentiometry whereas salivary copper and magnesium were determined by atomic absorption spectrophotometry whereas phosphates were determined by colorimetric method with use of molybdate. Statistical analysis was performed by use of χ2 test, Mann Whitney U test, analysis of covariance and Spearman´s correlation. Results: Significantly higher concentration of salivary chloride was detected in OLP patients in comparison to the controls (p=0.025). Furthermore, when the obtained results for salivary analytes were adjusted with respect to the salivary flow rate, increased levels of salivary potassium, sodium, chloride and total proteins were found in patients with OLP when compared to the controls (p=0.622 ; p=0.504 ; p=0.600 ; p=0.586). Concentrations of salivary analytes were not affected by smoking habit. Conclusions: Increased levels of salivary sodium, potassium and chloride are probably a result of significant differences in salivary flow rate between patients with OLP and controls and do not indicate increased salivary antimicrobial activity.
Projekt / tema: 065-0650445-0485, 062-0650446-0499
Izvorni jezik: ENG
Rad je citiran u
bazama podataka:
Scopus
Kategorija: Znanstveni
Znanstvena područja:
Dentalna medicina
URL cjelovitog teksta:
Google Scholar: Sialochemistry in Patients with Oral Lichen Planus
Upisao u CROSBI: brailo@sfzg.hr (brailo@sfzg.hr), 11. Stu. 2011. u 08:46 sati



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