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Pregled bibliografske jedinice broj: 590818

Časopis

Autori: Šoša, Ivan; Strenja-Linić, Ines; Bajek, Snježana; Cuculić, Dražen; Crnčević-Orlić, Željka; Grubešić, Aron; Cvijanović, Olga; Bosnar, Alan
Naslov: Corticosteroids provoke acute endothelial injury - An ideal ground for thrombosis in multiple sclerosis
( Corticosteroids provoke acute endothelial injury - An ideal ground for thrombosis in multiple sclerosis )
Izvornik: Journal of biological regulators & homeostatic agents (0393-974X) 26 (2012), 1; 131-134
Vrsta rada: pismo uredniku
Ključne riječi: acute endothelial injury; perivascular compartments; multiple sclerosis; corticosteroids
( acute endothelial injury; perivascular compartments; multiple sclerosis; corticosteroids )
Sažetak:
Despite the effect corticosteroids exert on blood clotting and the irrefutable impact of intracranial pressure decreasing shortly after lumbar puncture, a certain number of intracranial thromboses remain unexplained. Corticosteroids are useful in reducing the severity and duration of relapses of multiple sclerosis (MS). Several questions emerge concerning the reasons behind thrombosis occurring so sporadically, not pertaining to any rule, the most important of which regard the location and timing. We developed this hypothesis as an obverse to chronic endothelial injury theory which, only partially explains atherosclerosis development. We followed Virchow’s classical triad of conditions which are believed to be connected to the development of thrombosis. Although corticosteroids affect more than vessel wall injury, component of Virchow’s triad that has been our narrowest interest is exactly vessel wall injury.
Projekt / tema: 062-0000000-0073, 062-0000000-1352, 062-0620226-0208, 062-0620226-0207
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL cjelovitog teksta:
Google Scholar: Corticosteroids provoke acute endothelial injury - An ideal ground for thrombosis in multiple sclerosis
Upisao u CROSBI: isosa@medri.hr (isosa@medri.hr), 30. Kol. 2012. u 11:27 sati



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