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Pregled bibliografske jedinice broj: 591875

Časopis

Autori: Špalj, Stjepan; Mlacović Zrinski, Magda; Tudor Špalj, Vedrana; Ivanković Buljan, Zorana
Naslov: In-vitro assessment of oxidative stress generated by orthodontic archwires
Izvornik: American journal of orthodontics and dentofacial orthopedics (0889-5406) 141 (2012), 5; 583-589
Vrsta rada: članak
Ključne riječi: oxidative stress; genotoxicity; viability; orthodontic archwires
Sažetak:
Several metals undergo redox cycling, producing free radicals and generating oxidative stress. The purpose of this study was to investigate in-vitro oxidative stress of orthodontic archwires made of various alloys. Mouse fibroblast cells L929 were exposed to 6 types of archwires, and the concentration of the oxidative stress marker 8-hydroxy-2'- deoxyguanosine in DNA was evaluated. Trypan blue dye was used in the determination of cell viability and numbers. Standard nickel- titanium archwires generated the highest oxidative stress, significantly higher than all other wires and the controls (P <0.05), and coated nickel- titanium, copper-nickel-titanium, and cobalt- chromium were lower than nickel-titanium (P <0.05), but higher than titanium-molybdenum and the negative and absolute controls (P <0.05). Titanium-molybdenum and stainless steel generated the lowest stress. Nickel-titanium induced the lowest viability, lower than the negative and absolute controls and all other wires (P <0.05) except titanium-molybdenum. Stainless steel showed the highest viability. Nickel-titanium produced the highest inhibition of cell growth, higher than all samples (P <0.05) except the positive control and cobalt-chromium. The lowest inhibition was observed in stainless steel and titanium- molybdenum, lower than nickel-titanium, cobalt- chromium, and the positive control (P <0.05). All orthodontic archwires generate oxidative stress in vitro. Stainless steel archwires have the highest and nickel-titanium the lowest biocompatibility.
Projekt / tema: 065-0650444-0436
Izvorni jezik: ENG
Current Contents: DA
Citation Index: DA
Kategorija: Znanstveni
Znanstvena područja:
Stomatologija
Tiskani medij: da
URL Internet adrese: http://www.ajodo.org/article/S0889-5406%2812%2900133-3/abstract
Broj citata:
Altmetric:
DOI: 10.1016/j.ajodo.2011.11.020
Google Scholar: In-vitro assessment of oxidative stress generated by orthodontic archwires
Upisao u CROSBI: stjepan.spalj@uniri.hr (stjepan.spalj@uniri.hr), 6. Ruj. 2012. u 13:33 sati



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