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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 604512

Poglavlje/Rad u knjizi

Autori: Mravak Stipetić, Marinka
Naslov: Injectable and Mucosal Routes of Drug Administration
Knjiga: Update in dematologic drug therapy
Urednik/ci: Jasna Lipozenčić and coauthors
Izdavač: Academy of Medical Sciences of Croatia
Grad: Zagreb
Godina: 2012
Raspon stranica:: 269-278
Ukupni broj stranica u knjizi:: 497
ISBN: 978-953-6868-39-1
Ključne riječi: oral mucosa, drug administration
Sažetak:
The properties of oral mucosa (its accessibility, excellent blood supply and good permeability) make it an attractive and promising site for local and systemic drug delivery. The development of mucoadhesives, sustained drug release, permeability enhancers and drug delivery vectors supported with the novel technologies of molecular biology and nanotechnology enhances efficient drug delivery across the oral mucosa. Trabsmucosal drug delivery has many advantages in the treatment of oral and systemic diseases and for the patient himself ; it eases drug administration, improves patient compliance as compared to parenteral route, enables rapid onset of action and better systemic bioavailability of drug, bypasses first pass metabolism, enables sustained and protected drug delivery and lower dosage with higher efficacy. Therefore, oral mucosa provides exceptional treatment options for many local and systemic diseases allowing the use of a broad spectrum of drugs, even those the systemic use of which by other routes is associated with limitations.
Projekt / tema: 065-0982464-2532
Izvorni jezik: ENG
Kategorija: Ostalo
Znanstvena područja:
Stomatologija
Tiskani medij: da
Upisao u CROSBI: mbaranovi@sfzg.hr (mbaranovi@sfzg.hr), 22. Stu. 2012. u 10:09 sati



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