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Pregled bibliografske jedinice broj: 644285

Zbornik radova

Autori: Milin, Čedomila; Tota, Marin; Grebić, Damir; Jakovac, Hrvoje; Broznić, Dalibor; Marinić, Jelena; Čanadi Jurešić, Gordana; Radošević-Stašić, Biserka
Naslov: TRACE ELEMENTS DYSHOMEOSTASIS INDUCED BY EXPOSURE OF MICE TO GASOLINE VAPOR AND STRESS
Izvornik: Balkan Journal of Clinical Laboratory, XXI, 13, 1 / Danev, Stoyan ; Shipkov, Todor ; Svinarov, Dobrin A (ur.). - Budva : Balkan Clinical Laboratory Federation (Montenegrian Association) , 2013. 148-148.
ISSN: 1452-8258
Skup: 21st Meeting of Balkan Clinical Laboratory Federation
Mjesto i datum: Budva, Crna Gora, 25-28.09.2013
Ključne riječi: Gasoline inhalation; Stress; Metallothioneins I; Zinc; Copper; Magnesium; Brain; Lungs; Kidney; Liver
Sažetak:
To investigate the effects of air pollution related with gasoline/petrochemical industry the expression of metallothionein I (MT-I) mRNA and tissue metals were analyzed in organs of mice, exposed to the gasoline (G) vapor in laboratory conditions. Control groups consisted of intact mice and of those exposed in the metabolic chamber to fresh air. The data obtained by RT-PCR and inductively coupled plasma spectrometry have shown that exposure to G vapor leads to upregulation of MT-I mRNA in organs that receive a strong respiratory and olfactory input or participate in gasoline degradation and elimination (lungs, brain, kidney and liver). Simultaneously, the tissue content of Zn2+ decreased in the brain and the concentration of Cu2+ and Mg2+ in the brain, lungs, kidney and liver (p<0.001). Some of these changes were found also in mice closed in the metabolic chamber, pointing to the involvement of stress-induced mechanisms in the transcriptional regulation of MTs.
Rad je indeksiran u
bazama podataka:
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Domaća recenzija
Projekt / tema: 062-0621341-1337, 062-0621341-0061
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Temeljne medicinske znanosti
Upisao u CROSBI: Marin Tota (Marin.Tota@medri.hr), 30. Ruj. 2013. u 09:27 sati



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