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Pregled bibliografske jedinice broj: 671802

Časopis

Autori: Bajek, Snježana; Nikolić, Marina; Šoić-Vranić, Tamara; Bajek, Goran; Cvijanović, Olga; Starčević- Klasan, Gordana
Naslov: Influence of hyperbaric oxygen treatment on myogenic transcriptional factors of denervated rat muscle
Izvornik: Collegium antropologicum (0350-6134) 36 (2012), 1; 167-172
Vrsta rada: članak
Ključne riječi: hyperbaric oxygen; denervation; myogenic transcriptional factors; rat
Sažetak:
The aim of this study was to determine whether hyperbaric oxygen (HBO2) treatment influences the expression of transcriptional myogenic factors in denervated rat’s extensor digitorum longus muscle. Thus, expressing regulatory myogenic factors MyoD and myogenin were analyzed in denervated muscles (up to 30 days). Second group of denervated rats were afterwards treated with HBO2. Normal, innervated muscles were used as controls. Western blot analysis showed a significant upregulation of MyoD and myogenin proteins in denervated muscle during this period. Denervated muscles of rats exposed to HBO2 treatment had also significant upregulation of both transcriptional factors but the treatment had not altered their expression. The immunohistochemical analysis showed MyoD and myogenin protein expression through this period in the denervated, untreated muscles and in denervated muscles of rats treated with HBO2, too. One month denervation caused a reduction in muscle fiber cross-sectional area. The treatment with HBO2 had not reduced the degree of atrophy. The protocol of hyperbaric oxygenation (HBO) applied in this study had no beneficial effect either on transcriptional myogenic factors or on atrophy of denervated rat muscle.
Projekt / tema: 062-0620529-0517, 062-0000000-1352
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Social Science Citation Index (SSCI) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=117079
URL cjelovitog teksta:
Google Scholar: Influence of hyperbaric oxygen treatment on myogenic transcriptional factors of denervated rat muscle
Upisao u CROSBI: Snježana Bajek (snjezana.bajek@uniri.hr), 3. Sij. 2014. u 14:17 sati



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