Hrvatska znanstvena bibliografija (CROSBI)



Pregled bibliografske jedinice broj: 684910

Časopis

Autori: Đudarić, Luka; Zoričić Cvek, Sanja; Cvijanović, Olga; Šantić, Veljko; Marić, Ivana; Crnčević- Orlić, Željka; Bobinac, Dragica
Naslov: Expression of the BMP -2, -4 and -7 and their Antagonists Gremlin, Chordin, Noggin and Follistatin during Ectopic Osteogenesis
Izvornik: Collegium antropologicum (0350-6134) 37 (2013), 4; 1291-1298
Vrsta rada: članak
Ključne riječi: ectopic osteogenesis; BMP-2; BMP-4; BMP-7; gremlin; chordin; noggin; follistatin
Sažetak:
Molecular network of the osteogenic BMPs and extracellular inhibitors maintains homeostasis of the skeletal tissues. It is important to determine relationship between BMP-2, -4 and -7 and their inhibitors: gremlin, follistatin, chordin and noggin during normal osteogenesis. To determine their expression pattern we conducted investigation by inducing ectopic bone formation in rats. The results shown that levels of the BMP- 2 and BMP-4 expression in chondrocytes are similar to noggin and follistatin. The latter BMPs and inhibitors have increased levels of the expression at day 14th of the osteogenesis, which suggests their important roles in early phases of the chondrogenesis. Gremlin and chordin have shown increased levels of expression in late phase of chondrogenesis, which suggests their important role in regulation of the osteogenesis initiation. In this study, BMPs and inhibitors have the highest levels of expression at 21st day in osteocytes, which suggests their strong interactions in osteogenesis.
Projekt / tema: 062-0620226-0208, 062-0620226-0207, 062-0000000-3559
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Social Science Citation Index (SSCI) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti,Kliničke medicinske znanosti
URL Internet adrese: http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=174976
http://www.collantropol.hr/antropo/article/view/532
URL cjelovitog teksta:
Google Scholar: Expression of the BMP -2, -4 and -7 and their Antagonists Gremlin, Chordin, Noggin and Follistatin during Ectopic Osteogenesis
Upisao u CROSBI: Luka Đudarić (luka.dudaric@uniri.hr), 20. Sij. 2014. u 10:03 sati