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Pregled bibliografske jedinice broj: 69936


Autori: Aurer, Andrej; Aurer-Koželj, Jelena; Stavljenić-Rukavina, Ana; Kalenić, Smilja; Ivić-Kardum, Marija; Haban, Vesna
Naslov: Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase
Izvornik: Collegium Antropologicum (0350-6134) 23 (1999), 1; 117-124
Vrsta rada: članak
Rapidly progressive periodontitis (RPP) results from the interaction between the periodontal microflora and the host. Stress is believed to play an important role in determining host responses, and it has been proposed that hyperactivity of host defense mechanism significantly incresed tissue destruction tipical for this disease. During period of four months we have diagnosed 20 patients with acute RPP, all of them active participants in battles of the Croatian liberation war with posttraumatic stress disorder (PTSD) related simptoms. In these patients we analysed biochemical parameters in unstimulated saliva and performed microbiological analysis of periodontal pockets. These findings we compared with those of patients with adult periodontitis (AP), edentulous and healthy persons, none of whom participated in the war. Persons with AP had reduced concentrations of host humoral defense factors in saliva (C-reactive protein, C3 component of complement and alpha-2 macroglobulin), while patients with RPP had increased concentration of interleukin-6 (IL-6). IL-6 is released by host inflammatory cells and is mediator of bone resorption. Actinobacillus actinomycemcomitans and Peptostreptococcus were more frequently isolated in patients with RPP. We interpret these results as indicators of the importance of stress in causation of RPP, with host inflammatory hyperactivity playing an imporatnt role in tissue destruction, especially alveolar bone resorption, possibly caused by increased local levels of IL-6.
Projekt / tema: 065009
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
Social Science Citation Index (SSCI) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Dentalna medicina
URL cjelovitog teksta:
Google Scholar: Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase

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