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Pregled bibliografske jedinice broj: 759289

Zbornik radova

Autori: Anić, Kata; Mikolašević, Ivana; Orlić, Lidija; Devčić, Bosiljka; Jakopčić, Ivan; Rački, Sanjin
Naslov: THE IMPACT OF HEPATITIS C VIRAL INFECTION ON RENAL GRAFT AND PATIENT’S SURVIVAL – A SINGLE CENTER EXPERIENCE
Izvornik: Knjiga sažetaka ; 4th Congress of Nephrology of Bosnia and Herzegovina with international participation / Enisa Mesić (ur.). -
Skup: 4th Congress of Nephrology of Bosnia and Herzegovina with international participation
Mjesto i datum: Sarajevo, BIH, 22.-25.travnja, 2015.
Ključne riječi: hepatitis C; transplantacija
Sažetak:
INTRODUCTION: It remains controversial whether hepatitis C infection (HCV) alters log-term patients and renal graft survival. Our aim was to analyze the effects of HCV infection on patients and graft survival. METHODS: We retrospectively examined the 23-year (1990-2013) data of 471 renal transplant recipients (RTRs) mean age 50.2±14 years who were anti-HCV negative and 21 RTRs mean age 49±8 years who were anti-HCV positive at the time of transplantation. We compared graft and patients survival rates and causes of death and graft failure in HCV-positive and HCV-negative RTRs. RESULTS: There was no statistically significant difference between the two groups related to age or gender and due to the duration of dialysis treatment before the transplantation The mean posttransplant follow-up of 471 HCV negative RTRs was 61.1±59.3 months and for 21 HCV positive RTRs was 75.3±44.3 months (p=NS).There was no significant difference due to acute rejection crisis during the first-year of follow up (p=NS). The mean values of serum creatinine didn’t showed any significant differences after one-year, two-years and five-years of follow-up between the HCV negative RTRs and HCV positive RTRs (p=NS). In the HCV positive RTRs the main reason for graft loss was a chronic allograft nephropathy (CAN) (42.9%) and acute rejection crisis (42.9%). On the other hand, CAN was the cause of graft loss in the 44.1% of HCV negative RTRs, while acute rejection was the cause of graft loss in the 22% of RTRs that were anti-HCV negative. There were no significant differences in the patients survival between the HCV positive RTRs and HCV negative groups of our renal transplant recipients (38.1% vs. 22.9% ; p=NS). CONCLUSION: According to our experience, patients and graft survival were not affected by HCV infection. Anti-HCV positively should not preclude chronic renal failure patients from renal transplantation.
Vrsta sudjelovanja: Predavanje
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Upisao u CROSBI: Sanjin Rački (sanjin.racki@uniri.hr), 26. Tra. 2015. u 00:23 sati



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