crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 773961

Časopis

Autori: Štimac, Davor; Poropat, Goran; Hauser, Goran; Licul, Vanja; Franjić, Neven; Valković- Zujić, Petra; Milić, Sandra
Naslov: Early nasojejunal tube feeding versus nil-by-mouth in acute pancreatitis: A randomized clinical trial
( Early nasojejunal tube feeding versus nil-by-mouth in acute pancreatitis: A randomized clinical trial )
Izvornik: Pancreatology (1424-3903) 16 (2016), 4; 523-528
Vrsta rada: članak
Ključne riječi: acute necrotizing pancreatitis; complications; enteral nutrition; fasting; mortality
( acute necrotizing pancreatitis; complications; enteral nutrition; fasting; mortality )
Sažetak:
BACKGROUND/OBJECTIVES: There is substantial evidence of superiority of enteral nutrition (EN) to parenteral nutrition in acute pancreatitis (AP) treatment, but few studies evaluated its effectiveness compared to no intervention. The objective of our trial was to compare the effects of EN to a nil-by-mouth (NBM) regimen in patients with AP. METHODS: Patients with AP were randomized to receive either EN via a nasojejunal tube initiated within 24 h of admission or no nutritional support. Systemic inflammatory response syndrome (SIRS) was assessed as the primary outcome. Secondary outcomes included mortality, organ failure, local complications, infected pancreatic necrosis, surgical interventions, length of hospital stay, adverse events and inflammatory response intensity. Outcomes were compared using Student's t-test and Mann- Whitney U test as appropriate. RESULTS: 214 patients were randomized in total, 107 to each group. SIRS occurrence was similar between groups, with 48 (45%) versus 51 (48%), respectively (RR 0.94 ; 95% CI 0.71-1.26). No significant reduction of persistent organ failure (RR 0.81 ; 95% CI 0.52-1.27) and mortality (RR 0.59 ; 95% CI 0.28-1.23) was present in the EN group. There were no significant differences in other outcomes between the groups. When analyzing the occurrence of SIRS and mortality in subgroup of patients with severe disease no significant differences were noted. CONCLUSION: Our results showed no significant reduction of persistent organ failure and mortality in patients with AP receiving early EN compared to patients treated with no nutritional support (NCT01965873).
Projekt / tema: 062-0000000-0211
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Puni text rada: 773961.PIIS1424390316300175.pdf (tekst priložen 1. Svi. 2016. u 00:37 sati)
URL Internet adrese: http://www.pancreatology.net/article/S1424-3903(16)30017-5/abstract
Broj citata:
Altmetric:
DOI: 10.1016/j.pan.2016.04.003
URL cjelovitog teksta:
Časopis izlazi u samo elektroničkom izdanju: DA
Google Scholar: Early nasojejunal tube feeding versus nil-by-mouth in acute pancreatitis: A randomized clinical trial
Upisao u CROSBI: Goran Poropat (goran.poropat@uniri.hr), 30. Kol. 2015. u 22:09 sati



  Verzija za printanje   za tiskati


upomoc
foot_4