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Pregled bibliografske jedinice broj: 779867

Zbornik radova

Autori: Mavrinac, Vojko; Mikolašević, Ivana; Orlić, Lidija; Štimac, Davor; Milić, Sandra;
Naslov: THE IMPACT OF HEPATITIS C VIRAL INFECTION ON RENAL GRAFT AND PATIENT’S SURVIVAL – A SINGLE CENTER EXPERIENCE
Izvornik: Knjiga sažetaka 7. kongresa Hrvatskog gastroenterološkog društva
Skup: 7. kongres Hrvatskog gastroenterološkog društva
Mjesto i datum: Opatija, Hrvatska, 1.-4. listopada, 2015.
Ključne riječi: Renal allograft; hepatitis C; survival
Sažetak:
AIM: It remains controversial whether hepatitis C infection (HCV) alters log-term patients and renal graft survival. Our aim was to analyze the effects of HCV infection on patients and graft survival. METHODS: We examined the 23-year (1990-2013) data of 471 renal transplant recipients (RTRs) who were anti-HCV negative and 21 RTRs who were anti-HCV positive at the time of transplantation. We compared graft and patients survival rates and causes of death and graft failure in HCV-positive and HCV-negative RTRs. RESULTS: There was no significant difference due to acute rejection crisis during the first-year of follow up (p=NS). The mean values of serum creatinine didn’t showed any significant differences after one-year, two-years and five-years of follow-up between the HCV negative RTRs and HCV positive RTRs (p=NS). In the HCV positive RTRs the main reason for graft loss was a chronic allograft nephropathy (CAN) (42.9%) and acute rejection crisis (42.9%). On the other hand, CAN was the cause of graft loss in the 44.1% of HCV negative RTRs, while acute rejection was the cause of graft loss in the 22% of RTRs that were anti-HCV negative. There were no significant differences in the patients survival between the HCV positive RTRs and HCV negative groups of our RTRs (38.1%vs.22.9% ; p=NS). CONCLUSION: According to our experience, patients and graft survival were not affected by HCV infection. Anti-HCV positively should not preclude chronic renal failure patients from renal transplantation.
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Domaća recenzija
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Upisao u CROSBI: Sanjin Rački (sanjin.racki@uniri.hr), 5. Lis. 2015. u 11:09 sati



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