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Pregled bibliografske jedinice broj: 875539

Časopis

Autori: Cigić, Livia; Galić, Tea; Kero, Darko; Šimunić, Miroslav; Medvedec Mikić, Ivana; Kalibović Govorko, Danijela; Biočina Lukenda, Dolores
Naslov: The prevalence of celiac disease in patients with geographic tongue
Izvornik: Journal of oral pathology & medicine (0904-2512) 45 (2016), 10; 791-796
Vrsta rada: članak
Ključne riječi: antibodies to gliadin ; celiac disease ; duodenal biopsy ; geographic tongue ; tissue transglutaminase antibodies
Sažetak:
Background Geographic tongue (GT) is a benign inflammatory condition usually involving the dorsal surface and lateral borders of the tongue. Numerous etiological factors of GT have been suggested, including immunological factors ; genetic ; atopic or allergic predisposition ; emotional stress ; and hormonal disturbances. GT may also coexist as one of the possible manifestations of celiac disease (CD). Therefore, the aim of this study was to investigate the prevalence of CD, positive serologic tests for CD screening, and HLA-DQ presence in patients with GT. Methods Tissue transglutaminase antibodies (anti-tTG), antibodies against gliadin (AGA), and human leukocyte antigen (HLA) typing were assessed for 60 GT patients and 60 healthy control subjects. The duodenal biopsy was performed in patients with positive serologic tests. Results We found that 9 (15%) GT patients were positive for IgA tTG, and in those patients histological changes consistent with CD were confirmed by duodenal biopsy. Only two of them reported the presence of gastrointestinal symptoms. There were statistically significant differences between the GT patients and control group for immunoglobulin (Ig) A tTG (P = 0.03), IgG tTG (P = 0.04), IgA AGA (P = 0.04), and IgG AGA (P = 0.02). Conclusion The results of our study demonstrated the increased prevalence of CD in patients with GT. Therefore, the clinical oral examination should be considered a diagnostic tool, especially in atypical or silent forms of CD, since it may contribute to provide an early diagnosis.
Izvorni jezik: ENG
Current Contents: DA
Citation Index: DA
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti,Stomatologija
Tiskani medij: da
URL Internet adrese: http://onlinelibrary.wiley.com/doi/10.1111/jop.12450/abstract
Broj citata:
Altmetric:
DOI: 10.1111/jop.12450
Google Scholar: The prevalence of celiac disease in patients with geographic tongue
Upisao u CROSBI: Ivana Medvedec Mikić (ivana.medvedec@mefst.hr), 18. Svi. 2017. u 09:31 sati



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